Today, Marvel released a teaser for “Infested”, a series of backups that will run in Amazing Spider-Man starting in April with issue 659. While details are scarce, the teaser also mentions that these backups will apparently continue through at least Amazing Spider-Man #666 and lead into this summer’s Spider-Man event, titled “Spider-Island”.

From the press release:

Marvel is pleased to announce Infested, an all new series of short stories beginning in Amazing Spider-Man #659, leading into the biggest Spider-Man event of the year – Spider Island! And to set the stage, a whole cavalcade of superstar artists like Barry Kitson, Lee Garbett and Emma Rios join the red-hot Dan Slott for a Spidey spectacular that’ll have fans talking for years to come!

Infested is giving readers the first adumbrations of a threat that’s been slowly creeping toward Spidey’s life for decades,” said Marvel Senior Editor, Stephen Wacker. “Dan along with some guest artists set the readers on a dangerous course that leads right to Amazing Spider-Man #666…and beyond.”

Spider-Man has gone toe-to-toe with the biggest and baddest villains of the Marvel Universe, but nothing can prepare him for what he’ll be up against next! So pack your bags and get ready to jump on the road to the biggest Spider-Man event of the year starting with Infested, only inAmazing Spider-Man #659!

AMAZING SPIDER-MAN #659 (FEB110553)

Written by DAN SLOTT

Pencils and Cover by STEFANO CASELLI

Rated A .$3.99

FOC-4/4/11, On-Sale-4/27/11

I admit, I’m not quite sure what to make of this one. While the press release includes little hard information on the story, I confess I’ve been curious for some time what Marvel would do for Amazing Spider-Man #666. The obvious thing, especially given the events of the past few years, would be “something with Mephisto”, but that doesn’t seem to be the case. Indeed, the press release makes mention of a threat that has beenbuilding for decades, and knowing Slott’s penchant for drawing on continuity, this could easily be something that dates to the Lee/Ditko run. Heck, if Roger Stern hadn’t dropped the retcon bomb on them years ago, I’d probably suspect the aliens from the Tinkerer story way back in ASM #2! You’ll know more as soon as I do.